阿司匹林

阿司匹林

性質

Related Categories Core Bioreagents, Enzyme Inhibitors,Pharmacopoeia, Pharmacopoeia A-Z, Research Essentials,
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InChI Key   BSYNRYMUTXBXSQ-UHFFFAOYSA-N
mp   134-136 °C (lit.)
suitability   meets USP testing specifications
Featured Industry   Pharmaceutical (small molecule)
Gene Information   human ... ITGA2B(3674), PTGS1(5742), PTGS2(5743)

產品描述

Biochem/physiol Actions

通過抑制環(huán)氧化酶(前列腺素H合酶)，對COX-1亞型具有更高的選擇性，阻止前列腺素的產生。抗血栓作用是由于COX-1在血小板中的抑制作用，阻止血栓形成和血小板聚集。 對結直腸及其他實體腫瘤有化學預防作用。

Aspirin is an analgesic and antipyretic agent used in the treatment of fever and pain as in arthritis.[3] It is also associated with cardiovascular diseases.[3]

包裝

100, 500 g in poly bottle

Application

Aspirin has been used:
• as a stabilizer for blood during 13,14-dihydro-15-keto-prostaglandin F2α (PGFM) measurement[4]
• to evaluate cell viability of BV-2 microglial cell line[5]
• in morphogenesis assay[6]
 

General description

Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug.[1][2] It occurs as white crystalline powder[2] and is derived from salicylic acid.[2]